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1.Do most body builders use steroids? Yes they do. I would estimate that 100% of all professional
body builders use steroids and I would go as far to say that 90% of the
athletes that compete at the national amateur level use anabolic steroids.
Obviously, few of these athletes are admitting to steroid use, especially
at this point in time. Anabolic steroid use has never been more of an
antisocial behavior than it is right now, and the stigma is getting worse
all the time. Professional bodybuilders have to stand out and say that
they denounce the use of the very drugs that helped them achieve their
current status or they face serious consequences. The point of being a
professional body builder to begin with is that they have reached a level
of notoriety that is synonymous with marketability. 2.What is the difference between a cc, a ml, an I.U., a mg and a mcg? A cc (cubic centimeter) is equal to a ml (milliliter). They measure volume. For example if a vial contains 10 ml of liquid, that is the same as 10 ccs. A mg (milligram) measures the dose of a drug, A mg is equal to 1/1000 of a gram. A mcg (microgram) is equal to 1/1000 of milligram. An IU (International Unit) is also used to measure the dose of a preparation. 3.How do I inject and procedure? Injecting oil based steroids (deca durabolin, masteron, primobolan, sustanon, testosterone enathate) is done with intramuscular needle (1,5 inch long), while water based steroids testosterone suspension and winstrol depot) are injection with smaller and shorter subskin needle (0,5 inch long).
Step by step for vials
Step by step for ampoules
Injecting
What should I do to make sure I am injecting safely? First of all, it would likely take a full three ccs of air injected right into a vein to cause a fatality. Small air bubbles injected intramuscularly in an oil solution do not pose a hazard, yet it is a good practice to eliminate them anyway. Small air bubbles that appear in an oil solution after it is drawn into the syringe will slowly rise to the top of the syringe if held needle-side-up. This may take as long as ten minutes with some persistent tapping on the side of the case. After the air has all risen to the top of the solution, the stopper can be slightly pressed which expels the air from the syringe.
Counterfeit steroids are a bigger problem than you would believe, there are more counterfeit steroids in the market than you would think. These steroids offer no positive gains, and some give the side effects of real steroids. Taking counterfeit steroids is like injecting poison into your body, bad effects nothing positive. Using Excessive Dosages When taking steroids, the more you take is not always the best way to go. Taking excessive dosages has become a huge problem with steroids today. It isn't only dangerous, but studies have shown it to be ineffective. The body can only use a limited amount of the steroid so the extra is turned into estrogen by the body. Staying On Steroids Too Long In several cases, steroid users avoid waring signs telling them not to go on a cycle more than 8 to 12 weeks without an off period. If an off period is not taken, there is a higher chance for the negative effects of steroids to occur. If there is no off period the body does not have a chance to recover from the steroids, so more damage is done. This also is terrible for the kidneys and liver. Eating Poorly Many people ignore magazines and educators that explain eating as being an important asset to growing, but the truth is, eating healthy has a big effect on the body. When on steroids the user must comsume between 4000 and 7000 calories a day, not meaning eat only fat foods. The diet must be high in calories and protein, but low in fat. Training Incorrectly When on steroids the training must be intense and difficult. Instead of the usual weight that suits you, you must do excess weight and strenuous work for the best gains. The workout should involve the maximum weight possible, and make progress each time. Not Getting Regular Blood Tests Steroids are very dangerous and can cause great problems. Blood tests should be done often and regularly. When steroids are first taken many tests become elevated but will return to normal with in a few weeks. During the off period tests should also be done to make sure the body is recovering properly. If there is a problem with the Blood test, consult a doctor that you can trust. Using The Wrong Steroids Many athletes will increase their chances of getting negative effects when they take the wrong steroids. The strongest steroids that build more muscle mass, have the most side effects. These drugs should be avoided if possible, unless there is a reason to have an unbelievable gain. But these drugs are very toxic and we would recommend not taking them.
The side effects from steroids can be very serious and even fatal. But from the information we gathered in the past few years, it seems to me the side effects are not as serious as the media makes them out to be. Because of the media over exaggerating the side effects, this has turned many people way from steroids. There will only be short descriptions for the side effects now, and in the future we will add more to the side effects when we have time. Water Retention: This is most common from using steroids. It is a "puffiness" or swelling in the neck and facial areas. It is rather notable mainly if you know the person is on steroids. For example, we know someone that took steroids but we did not know it at the time. After we found out, if we looked his face we would wonder how we couldn't notice he was on roids before. It can be mild swelling or very serious, obvious swelling. Acne: Everyone knows about acne, and is one of the side effects we worry about the most for us. It is also a very common side effect, it can give acne to someone who has never had acne, and it can make acne worse for others. It can also appear in new places for a person, such as, the back and neck. There have been several users that have not received acne on the other hand. Gynecomastia: It may not sound familiar but most people have heard about it. It is the formation of breasts, or abnormally large glands. The first signs are lumps under the nipples, then will gradually grow to fatty tissue and increase in size. Aggression: Aggression, also know as "roid rages". Surprisingly, several athletes feel this is a positive effect. They often find they lift more, and are more intense during workouts. On the negative side, users find themselves fighting with family, friends, and co-workers with an uptight behaviour. Hypertension: High blood pressure is also a chance when taking steroids. Most athletes would not know if they had high blood pressure so it is suggested to get tests regularly. High blood pressure can lead to many more serious diseases. Cardiovascular Disease: Studies have shown that steroid use is a risk factor for heart disease. This is because steroids affect the cholesterol levels. Over a period of time the cholesterol builds up and clogs the arteries. Palpitations: Heart palpitations have been reported by a number of athletes on steroids. These may indicate an excited or elevated level of the central nervous system. Impotence: Impotence occurs when a user goes on and off steroids. When steroids are first used sexual interest increases because of the heightened frequency and duration of the erections. But eventually the opposite happens and no erections can be produced. Jaundice: A serious liver disease, which is found by an enlarged painful liver, yellowing of the eyes and skin, and flu like symptoms. This happens when athletes use high dosages of steroids.
Irritation of the stomach lining. Steroids can increase the production of stomach acid and lower the production of protective stomach mucus. This can irritate the lining of the stomach and may cause or aggravate a stomach ulcer. To reduce this side effect the tablets should be taken with meals or milk. Tell your doctor if you have indigestion, stomach pains or abdominal discomfort.
Fluid retention due to changed salt and water balance. You may notice that your ankles and/or fingers swell. Some people have a bloated feeling in the abdomen. This is usually only a problem with long-term treatment. Increased appetite. You may notice that you feel hungrier than usual while taking steroids, and this can make you want to eat more than usual. If you are concerned about weight gain speak to your doctor or contact Cancer BACUPs information service. Increased chance of infection and delayed healing of injuries. This happens mainly with high-dose or long-term treatment. Tell your doctor if you notice signs of infection (inflammation, redness, soreness or a temperature) or if cuts take longer than usual to heal. It is important to maintain good personal hygiene to prevent infection. Menstrual changes. Women may find that their periods become irregular or stop. Behavioural changes. You may notice mood swings, difficulty in sleeping and perhaps anxiety or irritability. These happen mainly with high-dose or long-term treatment and will stop when the steroid therapy ends. Tell your doctor about any behavioural changes which are worrying you. Difficulty in sleeping may be reduced by taking the steroids in the early part of the day, but discuss this with your doctor first. Less common side effects Eye changes. With long-term use of steroids, cataracts or glaucoma may develop. There is also an increased risk of eye infections. Tell your doctor if you notice any eye problems. Cushings syndrome. This is usually caused only by long-term use of steroids. It can cause acne, puffiness of the face, dark marks on the skin and facial hair in women. Cushings syndrome can be partially reduced by taking the steroids early in the morning, by taking them on alternate days instead of every day, or by reducing the dose, but discuss this with your doctor first. Muscle wasting. With very long-term use of steroids, wasting of leg muscles may occur. This can cause weakness. When the steroids are stopped some people experience muscle cramps for a short time. Osteoporosis. With very long-term use of steroids, calcium may be lost from the bones. This can result in pain (especially in the lower back), an increased susceptibility to fractures and loss of height. Other side effects include: enlarged prostate, premature hair loss, sterility, shortness, and head and stomach aches. 7. Anabolic Steroids and the Drug Development Pipeline Pat is responsible for launching several major product and innovation in the prohormone industry through LPJ Research and Ergopharm, including the first to release androstenedione, 1-AD, 6-OXO, 4-androstenediol, and 19-norandrostenediol. In addition, he is responsible for bringing innovative delivery systems to the prohormone market including HPB cyclodextrin, bioadhesive technology for sustained release, and sustained release sprays. I am told that articles on steroids are very popular. I guess there is some mystique surrounding chemicals that have the ability to dramatically transform one’s physique in a short period of time under the right conditions. You would think that people would get bored with this stuff after a while though, right? Well, apparently they don’t. Anyway, here is yet another steroid article. But what am I to write about? I had to think about this for a while and finally I decided to talk about the development of some steroids that you never heard of because they never made it to the market. I guess that by discussing this subject I can make a point about drug development in general that many people do not understand. You see, most people assume that all the great drugs developed by pharmaceutical companies must have ended up being sold to the public. If you develop a potent drug that has a good safety profile than naturally you gotta sell it, right? Well, that is not quite right at all. In fact, if you talk to pharmaceutical researchers they will tell you that only a very minor percentage of drugs that show great promise in the lab and/or clinical setting ever make it to market. The reasons for this can be many fold – a crowded market place, patent protection issues, prohibitively high cost of production, or lack of categorical sales can be a few. With the cost of getting a drug approved by the FDA for sale in the millions of dollars, as well as the high cost of drug marketing, you can see that some serious picking and choosing has to go on . The result is many very potent and promising drugs – anabolic steroids in this instance – falling through the cracks and never seeing the pharmacy shelves. Research and Development of anabolic steroidsFor you to fully appreciate the things I am going to discuss in this article you have to have a background on how anabolic steroids are screened for activity. As you know, anabolic steroids are derivatives of testosterone which share two types of activity – muscle building (deemed anabolic) and non muscle male sex hormone related activity (deemed androgenic). The goal of researchers in the golden age of anabolic steroid research (1935-1965) was to synthesize a compound which retained a high degree of anabolic activity coupled with a vastly diminished androgenic activity. This property was quantified using what is known as the Anabolic / Androgenic ratio (A/A ratio). The goal was not so much to produce a compound that was strongly anabolic, but rather the goal was to produce a compound with the highest possible A/A ratio. You must understand that the market for anabolic steroids was not bodybuilders / athletes but geriatric patients, patients recovering from surgery or injury, or those suffering from weakness or catabolism secondary to some other disease. These can include men and women, and even children. It was therefore paramount to avoid any virilizing effects when providing such people anabolic treatment, and so an anabolic agent with a very low A/A ratio was needed. To determine the A/A ratio, scientists utilized a test called the Rat Levator Ani Assay. In this test, scientists use two groups of castrated rats. The rats are castrated to remove any interfering influence from fluctuating natural androgen levels. The first group of rats are a control group that receives a placebo, while the second group receives the steroid (either by injection or orally). After a period of time (several days to weeks) the rats are sacrificed. Researchers then isolate three organs from each of the rats – the seminal vesicles, ventral prostate, and levator ani muscle. These organs are all weighed and a comparison of the active group to the placebo groups is made. The differences in weights for the seminal vesicles and ventral prostate represent androgenic activity, while the difference in the weight of the levator ani muscles in the control and active group represent anabolic activity. To give a landmark against which to gauge the relative activities of each steroid in this assay, a standard is used in some of the rats in the active group. This standard is usually testosterone, testosterone propionate, or 17alpha-methyltestosterone (MT) and the results obtained from the rats given this standard are designated an arbitrary number of 1 for anabolic activity and 1 for androgenic activity. Therefore these standard androgens are said to have an A/A ratio of 1. Make sense? To tell you the truth I understood this before but I think in the process of writing it down I just confused myself. Anyway, lets look at some steroids. Some SteroidsOf course out of all the work done during the 30 year heyday of anabolic steroid research came many wonderful compounds. Nandrolone was found to be a steroid with anabolic potency comparable to testosterone but with substantially diminished androgenic activity. Stanozolol (Winstrol) was found to be an orally active androgen with enhanced anabolic activity and reduced androgenic activity relative to MT. Methenolone (Primobolan) on the other hand had slightly diminished anabolic acitivity compared to testosterone, but due to its ultra-low androgenic activity possessed a very favorable A/A ratio. It also was found to be orally active. As I said before there are many great drugs that never made it to market and there are several possible reasons why these fell through the cracks. In the case of anabolic steroids specifically there are many powerful anabolics that simply did not have a favorable enough A/A ratio. In other words, they were too androgenic. This obviously is of little concern to male bodybuilders and athletes, but for doctors and patients in the clinical settings for which they were developed too much androgenic activity is a definite no-no. The following are several "lost" steroids. Some of them are very powerful anabolics with bad A/A ratios, but some of them are actually both very potent and have very good ratios. The toxicity of these are unfortunately largely unknown, but a good rule of thumb is the more androgenic and anabolic the more liver toxic. The BigFollowing are some compounds which have anabolic activity that rival many of the most potent anabolic compounds available in pharmacies across the world.
This is a steroid developed by Germans (I assume the infamous East German pharmaceutical company Jenapharm). There has to be something wrong with the numbers in the research because this purportedly has an A/A ratio of something like 121!! The specific numbers say that it has anabolic activity 7.3 times that of methandrostenolone (dianabol) while maintaining a seminal vesicle androgenic reading of 0.06 times that of methandrostenolone. I dunno…….
You steroid chemists out there will notice that this odd steroid is a sort of hybrid between trenbolone acetate and oxandrolone (anavar). The result is that it shares the same low A/A ratio of nandrolone while being 5 times as potent. Probably very expensive to manufacture though.
This orally active compound is a nandrolone derived compound with an 11beta-hydroxyl functional group. This functional group is usually not found on androgens but rather is a key characterisitic of glucocorticoids. In this case it does not seem to hurt the activity of this compound as it measures out with an anabolic activity 8.00 times and an androgenic activity of 2.60 that of MT. The A/A ratio is therefore a fair 3.07 The BadThese bad boys are at least as strong if not stronger than anything you could ever get your hands on.
You 1-AD aficionados may find this compound vaguely familiar. It is basically a methylated version of 1-testosterone. No, it is not legal for sale as a supplement. Yes, it is very potent - 9.1 to 16.0 times as anabolic as MT. It is mildly androgenic too – 1.0 to 2.2 times MT.
This compound was shown to be 10 times as anabolic as MT orally. By injection however it was only 1.3 times as anabolic. Don’t ask me to explain why. It is also somewhat androgenic – around 3 times as much as MT.
Look familiar? Its almost the same as the previous compound except there is an ethyl group coming off of carbon 13 in the steroid nucleus instead of the normal methyl group. This class of steroids is known as 13beta-ethyl gonanes. The 17alpha methyl is also replaced by an ethyl. The result of these alterations is a significant increase of the anabolic activity. The activity of this compound was compared to 17alpha-ethyl nortestosterone (a strange choice for a standard) and its anabolic potency was 14.5 times this standard. The androgenic activity was reduced to 0.86 the standard. The UglyThese compounds serve no practical purpose other than to strike fear into your liver.
This compound actually was sold as a drug at one time and is still used as a standard in in-vitro assays of androgens. It is an oral form of trenbolone basically and it was removed from the market because it had an unacceptable risk of hepatotoxicity. It is extremely anabolic – 120 to 300 times as anabolic compared to MT. It is also very androgenic – around 75 times that of MT. This is obviously not something that you should take without knowing what you are doing. On second thought, this is probably something you should not take at all.
Some sick scientist from Ciba thought that the preceding compound was not strong enough so he slapped a 7alpha-methyl group on it and came up with this monstrosity. Depending on the source it is either 100 times as anabolic as MT or – according to Ciba - 1000 times as anabolic as methandrostenolone (Dianabol). You have to laugh I guess.
Also from Ciba comes this mega-monster steroid. The only data I have on it is that it is 1000 times as potent as MT. I don’t know why Ciba thought it necessary to synthesize things like this because they obviously have no market potential. Just looking at the structure makes my liver ache. Summary You just looked at some pretty potent anabolic steroids but don’t
get the wrong idea. Just because something is 1000 times as potent as
d-bol does not mean that it will get you 1000 times as big as d-bol at
the same dose. No, what it means is that it takes a dose 1/1000th that
of a given dose dbol to get the same result. In fact, if you took d-bol
like doses of one of those monster steroids in the Ugly section you probably
would not get any gains. You would probably just end up sick.
Please email us your comments. Anadrol
Andriol Clenbuterol
Clomid Cytomel
Deca Durabolin Dianabol
(D-bol) Ephedrine
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